D-Limonene- Terpene Profile
With its sweet and citrusy odor, it is one of the most frequently used fragrances in cosmetic formulations.
With its sweet and citrusy odor, it is one of the most frequently used fragrances in cosmetic formulations. In addition, it's one of the most common terpenes in nature. It can be found in several food items but also in botanical insecticides and cleaning products.
Found in:
Orange
Medicinal qualities:
Anti-inflammatory
Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity
Gu, S. M., Kim, S. Y., Lamichhane, S., Hong, J.T., & Yun, J. (2019)
Anti-inflammatory
Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity
Gu, S. M., Kim, S. Y., Lamichhane, S., Hong, J.T., & Yun, J. (2019)
Wound Healing Effect of Essential Oil Extracted from Eugenia dysenterica DC (Myrtaceae) Leaves
Sandra Márcia Mazutti da Silva, Claudio Rodrigues Rezende Costa, Guilherme Martins Gelfuso, Eliete Neves Silva Guerra, Yanna Karla de Medeiros Nóbrega, Sueli Maria Gomes, Aline Pic-Taylor, Yris Maria Fonseca-Bazzo, Damaris Silveira, and Pérola de Oliveira Magalhães. (2019)
Wound Healing Effect of Essential Oil Extracted from Eugenia dysenterica DC (Myrtaceae) Leaves
Sandra Márcia Mazutti da Silva, Claudio Rodrigues Rezende Costa, Guilherme Martins Gelfuso, Eliete Neves Silva Guerra, Yanna Karla de Medeiros Nóbrega, Sueli Maria Gomes, Aline Pic-Taylor, Yris Maria Fonseca-Bazzo, Damaris Silveira, and Pérola de Oliveira Magalhães. (2019)
Anti-inflammatory
Antioxidative and Cholesterol-Lowering Effects of Lemon Essential Oil in Hypercholesterolemia-Induced Rabbits
Lee, H., Woo, M., Kim, M., Noh, J. S., & Song, Y. O. (2018)
Anti-inflammatory
Antioxidative and Cholesterol-Lowering Effects of Lemon Essential Oil in Hypercholesterolemia-Induced Rabbits
Lee, H., Woo, M., Kim, M., Noh, J. S., & Song, Y. O. (2018)
Anti-inflammatory
Limonene reduces hyperalgesia induced by gp120 and cytokines by modulation of IL-1 β and protein expression in spinal cord of mice
Piccinelli, A. C., Morato, P. N., Dos Santos Barbosa, M., Croda, J., Sampson, J., Kong, X., Konkiewitz, E. C., Ziff, E. B., Amaya-Farfan, J., & Kassuya, C. A. (2017)
Anti-inflammatory
Limonene reduces hyperalgesia induced by gp120 and cytokines by modulation of IL-1 β and protein expression in spinal cord of mice
Piccinelli, A. C., Morato, P. N., Dos Santos Barbosa, M., Croda, J., Sampson, J., Kong, X., Konkiewitz, E. C., Ziff, E. B., Amaya-Farfan, J., & Kassuya, C. A. (2017)
In Vitro
Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway
Bai, J., Zheng, Y., Wang, G., & Liu, P. (2016)
In Vitro
Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway
Bai, J., Zheng, Y., Wang, G., & Liu, P. (2016)
Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway
Bai J1, Zheng Y, Wang G, Liu P. (2016)
Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway
Bai J1, Zheng Y, Wang G, Liu P. (2016)
Anti-inflammatory
Antihyperalgesic and antidepressive actions of (R)-(+)-limonene, α-phellandrene, and essential oil from Schinus terebinthifolius fruits in a neuropathic pain model
Piccinelli, A. C., Santos, J. A., Konkiewitz, E. C., Oesterreich, S. A., Formagio, A. S., Croda, J., Ziff, E. B., & Kassuya, C. A. (2015)
Anti-inflammatory
Antihyperalgesic and antidepressive actions of (R)-(+)-limonene, α-phellandrene, and essential oil from Schinus terebinthifolius fruits in a neuropathic pain model
Piccinelli, A. C., Santos, J. A., Konkiewitz, E. C., Oesterreich, S. A., Formagio, A. S., Croda, J., Ziff, E. B., & Kassuya, C. A. (2015)
In Vitro
The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin
Bacanlı, M., Başaran, A. A., & Başaran, N. (2015)
In Vitro
The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin
Bacanlı, M., Başaran, A. A., & Başaran, N. (2015)
Anti-inflammatory
Anti-stress effects of d-limonene and its metabolite perillyl alcohol
d'Alessio, P. A., Bisson, J. F., & Béné, M. C. (2014)
Anti-inflammatory
Anti-stress effects of d-limonene and its metabolite perillyl alcohol
d'Alessio, P. A., Bisson, J. F., & Béné, M. C. (2014)
In Vivo & In Vitro
Skin repair properties of d-Limonene and perillyl alcohol in murine models
d'Alessio, P. A., Mirshahi, M., Bisson, J. F., Bene, M. C. (2014)
In Vivo & In Vitro
Skin repair properties of d-Limonene and perillyl alcohol in murine models
d'Alessio, P. A., Mirshahi, M., Bisson, J. F., Bene, M. C. (2014)
Skin repair properties of d-Limonene and perillyl alcohol in murine models
d'Alessio PA, Mirshahi M, Bisson JF, Bene MC1. (2014)
Skin repair properties of d-Limonene and perillyl alcohol in murine models
d'Alessio PA, Mirshahi M, Bisson JF, Bene MC1. (2014)
Anti-inflammatory
Evaluation of Anti-Inflammatory Activity of Citrus latifolia Tanaka Essential Oil and Limonene in Experimental Mouse Models
Kummer, R., Fachini-Queiroz, F. C., Estevão-Silva, C. F., Grespan, R., Silva, E. L., Bersani-Amado, C. A., & Cuman, R. K. (2013)
Anti-inflammatory
Evaluation of Anti-Inflammatory Activity of Citrus latifolia Tanaka Essential Oil and Limonene in Experimental Mouse Models
Kummer, R., Fachini-Queiroz, F. C., Estevão-Silva, C. F., Grespan, R., Silva, E. L., Bersani-Amado, C. A., & Cuman, R. K. (2013)
Anti-inflammatory
Protective effects of D-limonene on lipid peroxidation and antioxidant enzymes in streptozotocin-induced diabetic rats
Murali, R., Karthikeyan, A., & Saravanan, R. (2013)
Anti-inflammatory
Protective effects of D-limonene on lipid peroxidation and antioxidant enzymes in streptozotocin-induced diabetic rats
Murali, R., Karthikeyan, A., & Saravanan, R. (2013)
In Vitro
Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells
Jia, S. S., Xi, G. P., Zhang, M., Chen, Y. B., Lei, B., Dong, X. S., & Yang, Y. M. (2013)
In Vitro
Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells
Jia, S. S., Xi, G. P., Zhang, M., Chen, Y. B., Lei, B., Dong, X. S., & Yang, Y. M. (2013)
In Vivo & In Vitro
Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans
d'Alessio, P. A., Ostan, R., Bisson, J. F., Schulzke, J. D., Ursini, M. V., & Béné, M. C. (2013)
In Vivo & In Vitro
Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans
d'Alessio, P. A., Ostan, R., Bisson, J. F., Schulzke, J. D., Ursini, M. V., & Béné, M. C. (2013)
In Vitro
Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer
Yang, H., & Dou, Q. P. (2010)
In Vitro
Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer
Yang, H., & Dou, Q. P. (2010)
In Vitro
Limonene suppresses lipopolysaccharide-induced production of nitric oxide, prostaglandin E2, and pro-inflammatory cytokines in RAW 264.7 macrophages
Yoon, W. J., Lee, N. H., & Hyun, C. G. (2010)
In Vitro
Limonene suppresses lipopolysaccharide-induced production of nitric oxide, prostaglandin E2, and pro-inflammatory cytokines in RAW 264.7 macrophages
Yoon, W. J., Lee, N. H., & Hyun, C. G. (2010)
Anti-inflammatory
Effects of the essential oil from Citrus aurantium L. in experimental anxiety models in mice
de Moraes Pultrini, A., Galindo, L. A., Costa, M. (2006)
Anti-inflammatory
Effects of the essential oil from Citrus aurantium L. in experimental anxiety models in mice
de Moraes Pultrini, A., Galindo, L. A., Costa, M. (2006)
Anti-inflammatory
Anxiolytic and sedative effects of extracts and essential oil from Citrus aurantium L
Carvalho-Freitas, M. I., & Costa, M. (2002)
Anti-inflammatory
Anxiolytic and sedative effects of extracts and essential oil from Citrus aurantium L
Carvalho-Freitas, M. I., & Costa, M. (2002)
Anti-inflammatory
Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) N.E. Brown
Gurgel do Vale, T., Couto Furtado, E., Santos Jr., J. G., & Viana, G. S. B. (2002)
Anti-inflammatory
Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) N.E. Brown
Gurgel do Vale, T., Couto Furtado, E., Santos Jr., J. G., & Viana, G. S. B. (2002)
In Vitro
Limonene-induced regression of mammary carcinomas
Haag, J. D., Lindstrom, M. J., & Gould, M. N. (1992)
In Vitro
Limonene-induced regression of mammary carcinomas
Haag, J. D., Lindstrom, M. J., & Gould, M. N. (1992)
State of Matter
Liquid
Boiling Point
176 °C°C
High Beta-Myrcene strain-specific terpene formulations:
Pineapple Express
Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience
Pineapple Express
Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience
Pineapple Express
Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience
Pineapple Express
Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience
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