Synergy Research
Effects come from combinations,
not single molecules.
A real botanical effect is the sum of dozens of compounds acting together. Eybna models that entourage at the receptor level, the combinatorial space a single-molecule approach can never see.
OUR METHOD
The synergy thesis
A flower can contain 140+ terpenes; nature has produced over 50,000. The feeling a plant delivers, calm, lift, focus, is never a single molecule. It is a blend acting across multiple receptors at once.
Most of the industry still formulates around single “hero” compounds because that’s what’s easy to measure. It misses the interactions that actually produce the outcome. Eybna was built on the opposite premise.
Why it matters
Why single-molecule formulation misses it.
Optimize one molecule and you optimize one number. Optimize a system and you can tune the whole experience: onset, intensity, the balance between two effects, the way a flavor lands first sip or puff to last
This is the difference between a flavor note that hints at an effect and an ingredient engineered to deliver it. It’s also why our 37-terpene BUUZ® formulation beat Givaudan’s Zensera™ to win Ingredient Idol 2025.
platform | layer 01
AI & In-Silico
Before a single drop is mixed, BNA™ models how each compound meets each receptor, screening thousands of molecules computationally, so the lab only ever tests the candidates most likely to work.
Why it matters
Modeling biology at the molecular level
In-silico is where speed comes from. Molecular docking predicts how strongly a compound binds a target receptor; molecular dynamics simulates how that interaction behaves over time. Run across 2,200+ botanical compounds and 22+ receptors, this turns a brief into a ranked shortlist in hours instead of months.
Our stack runs multiple engines for cross-validation, not a single black box:
Predicted, then ranked
From thousands of compounds to a shortlist.
2,200+ plant compounds modeled against 22+ human receptors, predicted, validated, and confirmed on real people.
01
Dock
Predict binding strength between every candidate compound and the target receptor.
02
Simulate
Model the interaction over time to filter out unstable or implausible binders.
03
Rank
Score and shortlist, handing the lab a small, high-probability candidate set.
Speed as a moat
From trend signal to formula in 30 days.
Our in-silico platform turns emerging trends into market-ready ingredients within days, before traditional flavor houses can even scope the project.
When a new strain or flavor trend appears, we formulate against it the same week and put a sample in a customer's hands before a flavor house has scoped the brief.
Flavor houses are built around 6–18-month projects and large minimums. BNA™ is built around 30 days and 250 mL. That is structural, not a promotion.
platform | layer 02
Receptor Intelligence
A computational prediction is only a hypothesis until a human cell agrees. Layer 02 runs live in-vitro assays that confirm exactly how a compound engages each receptor, producing mechanism-of-action data that flavor houses do not generate.
Measured on human cells
We run functional assays on human cell lines to measure receptor response directly, not in animals, not by proxy. Three readouts tell us how, and how strongly, a compound acts:
The result is a validated map from compound to receptor to outcome, for sleep, focus, recovery and mood, built over a decade of assays, and ours.
The receptor map
Receptors we target, and what they do.
Representative targets from a panel of 22+ human receptors. Full assay data available under NDA.
platform | layer 03
Human Brainwave Measurement
Anyone can claim a terpene “helps you relax.” We can show which receptor it engages, how strongly, and the human data behind it. That’s the difference between folklore and a functional claim a brand can stand behind.
It’s also what makes Eybna INSIDE™ credible: when a wellness brand needs to explain why a product works, the answer comes from this map.
VALIDATION & SAFETY
The right claim for the right market, by default.
Compliance, built in
Shipped, compliant, certified.
BNA™ carries a regulatory layer across categories and territories, so every formula ships ready for where it’s going.
Markets
Each formula is mapped to the regulatory requirements of its destination market, helping ensure the right ingredients, claims, and documentation are in place from the start.
Categories
Compliance is tailored to the product format, accounting for the distinct safety, formulation, labeling, and claims requirements of each category.
Why it’s a moat
Globally credited.
FSSC 22000, GMP, ISO 9001 and OU Kosher across three production sites. FEMA GRAS ingredients. Per-market dossiers for the US, EU, UK, Japan and Australia, generated with the formula. Global brands are raising the bar on flavor provenance; Eybna was built above it.
Start with a sample
Tell us the feeling you want your product to deliver. We'll formulate it in 30 days.