D/L-Menthol - Terpene Profile

Menthol is mainly produced from mint oils and is commonly used in the food and pharma industry.

Menthol is mainly produced from mint oils and  is commonly used in the food and pharma industry. It has a peppermint-like aroma and creates a cooling sensation when applied to skin and mucosal surfaces.  There is a difference in the molecular structure between D- and L-menthol, which can be simplified by thinking of these molecules as the mirror image of one another. D-menthol has less cooling effects than its “mirrored sibling”.

Found in:

Mint

Mint plant

Medicinal qualities:

In Vivo

L-menthol exhibits antidepressive-like effects mediated by the modification of 5-HTergic, GABAergic and DAergic systems

Wang, W., Jiang, Y., Cai, E., Li, B., Zhao, Y., Zhu, H., Zhang, L., & Gao, Y. (2019)

In Vivo

L-menthol exhibits antidepressive-like effects mediated by the modification of 5-HTergic, GABAergic and DAergic systems

Wang, W., Jiang, Y., Cai, E., Li, B., Zhao, Y., Zhu, H., Zhang, L., & Gao, Y. (2019)

In Vivo

Prevention of colonic spasm using l-menthol in colonoscopic examination

Yoshida, N., Naito, Y., Hirose, Y., Ogiso, K., Inada, Y., Fernandopulle, N., Kamada, K., Katada, K., Uchiyama, K., Handa, O., Takagi, T., Konishi, H., Yagi, N., Wakabayashi, N., Yanagisawa, A., & Itoh, Y. (2014)

In Vivo

Prevention of colonic spasm using l-menthol in colonoscopic examination

Yoshida, N., Naito, Y., Hirose, Y., Ogiso, K., Inada, Y., Fernandopulle, N., Kamada, K., Katada, K., Uchiyama, K., Handa, O., Takagi, T., Konishi, H., Yagi, N., Wakabayashi, N., Yanagisawa, A., & Itoh, Y. (2014)

In Vitro / Antimicrobial

Mechanisms of Antibacterial Action of Three Monoterpenes

Trombetta, D., Castelli, F., Sarpietro, M. G., Venuti, V., Cristani, M., Daniele, C., Saija, A., Mazzanti, G., & Bisignano, G. (2005)

In Vitro / Antimicrobial

Mechanisms of Antibacterial Action of Three Monoterpenes

Trombetta, D., Castelli, F., Sarpietro, M. G., Venuti, V., Cristani, M., Daniele, C., Saija, A., Mazzanti, G., & Bisignano, G. (2005)

In Vivo

Local Anaesthetic Activity of (+)- and (-)-Menthol

Galeotti, N., Ghelardini, C., Di Cesare Mannelli, L., Mazzanti, G., Baghiroli, L., & Bartolini, A. (2000)

In Vivo

Local Anaesthetic Activity of (+)- and (-)-Menthol

Galeotti, N., Ghelardini, C., Di Cesare Mannelli, L., Mazzanti, G., Baghiroli, L., & Bartolini, A. (2000)

D/L-Menthol molecular structure

State of Matter

Solid

Boiling Point

216°C

High Beta-Myrcene strain-specific terpene formulations:

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Woman with eyes closed, glowing aroma lines across her face

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