Caryophyllene Oxide - Terpene Profile

Caryophyllene Oxide has a sweet, woody aroma and is mainly found in lemon balm and geranium.

Caryophyllene Oxide has a sweet, woody aroma and is mainly found in lemon balm and geranium. It is the product of the oxidation of Caryophyllene. Furthermore, it’s the component responsible for cannabis identification by drug-sniffing dogs. It is believed to be the only terpene in cannabis that has the ability to successfully bind with CB2 receptor. This unique skill makes it highly beneficial for medicinal uses, However, Caryophyllene Oxide only has a few known medical benefits. 

Found in:

Black Pepper

Black Pepper plant

Medicinal qualities:

In Vitro / Anti Tumor

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

Park, K. R., Nam, D., Yun, H. M., Lee, S. G., Jang, H. J., Sethi, G., Cho, S. K., & Ahn, K. S. (2011)

In Vitro / Anti Tumor

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

Park, K. R., Nam, D., Yun, H. M., Lee, S. G., Jang, H. J., Sethi, G., Cho, S. K., & Ahn, K. S. (2011)

In Vivo / Analgesic & Anti-inflammatory

Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark

Chavana, M. J., Wakteb, P. S., & Shinde, D.B. (2010)

In Vivo / Analgesic & Anti-inflammatory

Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark

Chavana, M. J., Wakteb, P. S., & Shinde, D.B. (2010)

In Vitro / Antimicrobial

Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis

Yang, D., Michel, L., Chaumont, J. P., & Millet-Clerc, J. (1999)

In Vitro / Antimicrobial

Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis

Yang, D., Michel, L., Chaumont, J. P., & Millet-Clerc, J. (1999)

Caryophyllene Oxide molecular structure

State of Matter

Solid

Boiling Point

279°C

High Beta-Myrcene strain-specific terpene formulations:

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Pale yellow flavor bottle

Pineapple Express

Bright pineapple and citrus notes blend with earthy pine for a vibrant, tropical, and refreshing aroma experience

Woman with eyes closed, glowing aroma lines across her face

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